To travel from Brighton to Manchester one can take several options including train, bus and plane. The fastest train from Brighton to Manchester takes around 3 hours and 49 minutes which usually involves one change of train. Whereas, if you board Brighton to Manchester bus you need to spend on average 8h40m on the road to cover the 204 miles between Brighton and Manchester. Though the journey by bus is longer, it is usually less expensive than train or plane. The earliest Brighton to Manchester train is usually scheduled to depart from Brighton station around 05:23 and the last train is around 00:10. All trains Brighton to Manchester arrives at either Manchester Piccadilly station or Manchester Oxford train station. Brighton Manchester train includes all fare types such as advance, off peak, anytime, singles and returns. So, find out what are the best options available on the line between Brighton and Manchester now!